What’s causing all your period issues? Find out now


May 26, 2023

Causes and Treatments for Premature Ovarian Insufficiency

with podcast guest

Dr. Mandy Leonhardt


Dr. Mandy Leonhardt is a fully qualified and GMC-registered GP. She is particularly interested in women’s health, nutrition, and healthy aging, and her ongoing professional development reflects this passion. She offers a private clinic specializing in the holistic assessment and individualized treatment of hormonal imbalances at every stage of a woman’s life: Premenstrual Syndrome (PMS), Perimenopause, and Menopause. She aims to give women the best evidence-based, personally tailored advice about treatment options for hormonal imbalances and healthy aging.

In this episode, Dr. Mandy and I dive into a condition called premature ovarian insufficiency, also known as primary ovarian insufficiency or premature ovarian failure. Dr. Mandy sheds light on what POI is, why it’s so underdiagnosed, the causes of this condition, why POI is hard to treat, and so much more!



  • Understanding primary ovarian insufficiency (POI) and its effects
  • The two key roles our ovaries play in our body
  • Recognizing that your period is a vital sign
  • Reasons why some young girls never get their period
  • The overlap between autoimmune conditions and POI
  • The lack of research on women’s health and the normalizing of period issues
  • The use of birth control pills as a bandaid solution
  • The stigma of hormone replacement therapy
  • How hysterectomy can contribute to premature ovarian insufficiency
  • Tuning into what your menstrual cycle might be telling you
  • Common symptoms associated with POI
  • Estrogen’s role in bone density, cardiovascular health, and more
  • How POI is diagnosed
  • Treatment options and the importance of the lifestyle aspect of managing POI
  • Why a personalized approach with close monitoring is crucial
  • How to improve sleep quality and gut and mental health to alleviate symptoms of POI
  • Why POI is not the same as early menopause and whether it can be improved
  • Dr. Mandy’s thoughts on experimental treatments for ovarian rejuvenation
  • Resources that can support you


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period lovin' content?

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Bonuses Include: The Fix Your Period Workbook to Use Alongside the Book
The Fix Your Period Toolkit includes a series of handouts on vaginal steaming, how to use CBD for your menstrual cycle problems, seed cycling, how to use castor oil packs to support your period and fertility, and how to live in harmony with your cycle!

Medical Disclaimer
Information in this post and on this web site is provided for informational purposes only. The information is a result of practice experience and research by the author. This information is not intended as a substitute for the advice provided by your physician or other healthcare professional or any information contained on or in any product label or packaging. Do not use the information on this web site for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. Always speak with your physician or another healthcare professional before taking any medication or nutritional, herbal, or homeopathic supplement, or using any treatment for a health problem. This post may contain affiliate links. Click here to read my affiliate disclosure.